The present disclosure relates to a high-voltage generator with multi-stage selection in low-voltage transistor process which include a boosted circuit, a plurality of switch and a feedback circuit. The boosted circuit includes multiple charge pump, so that can generate a DC output voltage higher or lower than the input signal. Turning on or turning off each switch controlled by a control signal respectively. Both ends of the circuit is connected to the output end of the high-voltage generator and charge pumps. By controlling the turning on or turning off each switch, it determines the magnitude of the boost and it also can ensure that switches will not be damaged due to excessive voltage difference.