Invention Grant
- Patent Title: Azophenols as ERG oncogene inhibitors
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Application No.: US15561626Application Date: 2016-09-09
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Publication No.: US10238639B2Publication Date: 2019-03-26
- Inventor: Albert L. Dobi , Clifton L. Dalgard , Shiv K. Srivastava
- Applicant: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Applicant Address: US MD Bethesda
- Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- Current Assignee Address: US MD Bethesda
- Agency: Morgan, Lewis & Bockius LLP
- International Application: PCT/US2016/051098 WO 20160909
- International Announcement: WO2017/044844 WO 20170316
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K31/44 ; A61P35/00 ; C07C245/00 ; C07C245/02 ; C07C245/04 ; A61K31/4402 ; C07D277/50
Abstract:
Selective azophenol inhibitors of a wild type or an altered ERG protein expression are described, where the inhibitors represent a compound of Formula (I) or Formula (II) wherein X, X1, X2, X3, X4 and X5, R1 through R4 and R9 are as described.
Public/Granted literature
- US20180169074A1 Azophenols as ERG Oncogene Inhibitors Public/Granted day:2018-06-21
Information query
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