Invention Grant
- Patent Title: Mutant organophosphorus acid anhydrolases and uses thereof
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Application No.: US15703123Application Date: 2017-09-13
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Publication No.: US10238904B1Publication Date: 2019-03-26
- Inventor: Mark A Guelta , Melissa M. Dixon , Steven P Harvey
- Applicant: U.S. Army Edgewood Chemical Biological Center
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Secretary of the Army
- Current Assignee: The United States of America as Represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Ulysses John Biffoni
- Main IPC: A61K38/46
- IPC: A61K38/46 ; C12N9/14 ; A62D3/02 ; C12N9/16 ; A62D101/02 ; A62D101/26
Abstract:
Disclosed herein are non-wild-type organophosphorus acid anhydrolases having two site mutations, methods of production, and methods of use to effectively degrade toxic chemicals such as ((RS)-Propan-2-yl methylphosphonofluoridate) (Sarin) and other organophosphorus compounds.
Information query
IPC分类:
