Invention Grant
- Patent Title: Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
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Application No.: US15406128Application Date: 2017-01-13
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Publication No.: US10239846B2Publication Date: 2019-03-26
- Inventor: Esther Martinborough , Marcus F. Boehm , Adam Richard Yeager , Junko Tamiya , Liming Huang , Enugurthi Brahmachary , Manisha Moorjani , Gregg Alan Timony , Jennifer L. Brooks , Robert Peach , Fiona Lorraine Scott , Michael Allen Hanson
- Applicant: Celgene International II Sàrl
- Applicant Address: CH Couvet
- Assignee: CELGENE INTERNATIONAL II SÀRL
- Current Assignee: CELGENE INTERNATIONAL II SÀRL
- Current Assignee Address: CH Couvet
- Agency: Seed Intellectual Property Law Group LLP
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; A61K45/06 ; A61K31/5377 ; A61K31/496 ; A61K31/454 ; A61K31/427 ; C07D271/06 ; C07D413/10 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07C245/14 ; C07C255/58 ; C07C311/13
Abstract:
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
Public/Granted literature
- US20170320839A1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS Public/Granted day:2017-11-09
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