Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
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Application No.: US15659926Application Date: 2017-07-26
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Publication No.: US10239867B2Publication Date: 2019-03-26
- Inventor: Sara S. Hadida Ruah , Peter D. J. Grootenhuis , Fredrick Van Goor , Jinglan Zhou , Brian Bear , Mark T. Miller , Jason McCartney , Mehdi Michel Jamel Numa , Xiaoqing Yang
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D403/12 ; C07D405/14 ; C07D471/04 ; C07D487/04 ; G01N33/50 ; G01N33/68 ; C07B59/00
Abstract:
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20180162842A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Public/Granted day:2018-06-14
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