- Patent Title: Sulfonamide compounds as voltage-gated sodium channel modulators
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Application No.: US15757103Application Date: 2016-09-03
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Publication No.: US10239869B2Publication Date: 2019-03-26
- Inventor: Vidya Ramdas , Rajeshkumar Maganlal Loriya , Moloy Banerjee , Pradeep Rangrao Patil , Advait Arun Joshi , Laxmikant Shamlal Datrange , Deepak Sahebrao Walke , Talha Hussain Khan , Amit Kumar Das , Ganesh Navinchandra Gote , Vaibhav Madhukar Kalhapure , Venkata P. Palle , Rajender Kumar Kamboj
- Applicant: LUPIN LIMITED
- Applicant Address: IN Mumbai, Maharashtra
- Assignee: LUPIN LIMITED
- Current Assignee: LUPIN LIMITED
- Current Assignee Address: IN Mumbai, Maharashtra
- Agency: Merchant & Gould P.C.
- Priority: IN3420/MUM/2015 20150904; IN201621011342 20160331
- International Application: PCT/IB2016/055291 WO 20160903
- International Announcement: WO2017/037682 WO 20170309
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; A61P29/00

Abstract:
The present invention relates to sulfonamide compounds Formula (I) wherein the substituents are as described herein, and their use in a medicine for the treatment of diseases, disorders associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. It further relates to the compounds herein and their pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof useful in treating diseases, disorders, syndromes and/or conditions associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. The invention also relates to process for the preparation of the compounds of the invention.
Public/Granted literature
- US20180186777A1 SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS Public/Granted day:2018-07-05
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