Invention Grant
- Patent Title: Insecticidal proteins
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Application No.: US15148482Application Date: 2016-05-06
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Publication No.: US10239921B2Publication Date: 2019-03-26
- Inventor: Hope Hart , Jeng Shong Chen , Cheryl M. Defontes , Frederick Walters
- Applicant: Syngenta Participations AG
- Applicant Address: CH Basel
- Assignee: Syngenta Participations AG
- Current Assignee: Syngenta Participations AG
- Current Assignee Address: CH Basel
- Agent Gregory W. Warren
- Main IPC: C07K14/325
- IPC: C07K14/325 ; C12N15/82 ; A01N63/02

Abstract:
Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
Public/Granted literature
- US20160304569A1 INSECTICIDAL PROTEINS Public/Granted day:2016-10-20
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