Invention Grant
- Patent Title: Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis
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Application No.: US13505150Application Date: 2010-11-05
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Publication No.: US10239937B2Publication Date: 2019-03-26
- Inventor: V. Michael Holers , Antonio M. Risitano
- Applicant: V. Michael Holers , Antonio M. Risitano
- Applicant Address: US MA Boston
- Assignee: Alexion Pharmaceuticals, Inc.
- Current Assignee: Alexion Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- International Application: PCT/US2010/055745 WO 20101105
- International Announcement: WO2011/057158 WO 20110512
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K14/47 ; C07K14/705 ; A61K38/17
Abstract:
Methods for treating subjects having complement-mediated hemolytic disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and other hemolytic anemias, the method comprising administering an effective amount of a composition that inhibits the activity of the complement alternative pathway.
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