Invention Grant
- Patent Title: Method for preparing induced paraxial mesoderm progenitor (IPAM) cells and their use
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Application No.: US14342251Application Date: 2012-08-29
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Publication No.: US10240123B2Publication Date: 2019-03-26
- Inventor: Olivier Pourquie , Jérôme Chal
- Applicant: Olivier Pourquie , Jérôme Chal
- Applicant Address: FR Paris FR Paris FR Strasbourg FR Paris
- Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE),UNIVERSITE DE STRASBOURG,ASSOCIATION FRANCAISE CONTRE LE MYOPATHIES
- Current Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE),UNIVERSITE DE STRASBOURG,ASSOCIATION FRANCAISE CONTRE LE MYOPATHIES
- Current Assignee Address: FR Paris FR Paris FR Strasbourg FR Paris
- Agency: Polsinelli PC
- Agent Christopher M. Cabral
- Priority: EP11306080 20110829; EP12305610 20120601
- International Application: PCT/EP2012/066793 WO 20120829
- International Announcement: WO2013/030243 WO 20130307
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/0735 ; C12N5/0775 ; C12N5/077
Abstract:
The present invention relates to an ex vivo method for preparing induced paraxial mesoderm progenitor (iPAM) cells, said method comprising the step of culturing pluripotent cells in an appropriate culture medium comprising an effective amount of an activator of the Wnt signaling pathway and an effective amount of an inhibitor of the Bone Morphogenetic Protein (BMP) signaling pathway.
Public/Granted literature
- US20140363886A1 METHOD FOR PREPARING INDUCED PARAXIAL MESODERM PROGENITOR (IPAM) CELLS AND THEIR USE Public/Granted day:2014-12-11
Information query
