Invention Grant
- Patent Title: Biosynthesis of forskolin and related compounds
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Application No.: US16031492Application Date: 2018-07-10
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Publication No.: US10240173B2Publication Date: 2019-03-26
- Inventor: Björn Hamberger , Birger Lindberg Møller , Eirini Pateraki , Johan Andersen-Ranberg , Niels Bjerg Jensen
- Applicant: University of Copenhagen , Danmarks Tekniske Universitet , Evolva SA
- Applicant Address: DK Copenhagen DK Lyngby CH Reinach
- Assignee: University of Copenhagen,Danmarks Tekniske Universitet,Evolva SA
- Current Assignee: University of Copenhagen,Danmarks Tekniske Universitet,Evolva SA
- Current Assignee Address: DK Copenhagen DK Lyngby CH Reinach
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: DK201400057 20140131; DK201470380 20140623; DK201470536 20140903
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P17/06 ; C12P5/00 ; C12N9/02
Abstract:
The invention described materials and methods for producing oxidized 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R-MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.
Public/Granted literature
- US20190010527A1 Biosynthesis of Forskolin and Related Compounds Public/Granted day:2019-01-10
Information query
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