A “Pipe and Strap Operating Drive System” (PSODS) is disclosed which efficiently and accurately positions a blocker, or door mechanism, over an opening that is of exact or similar profile and dimensions as the door mechanism. In the preferred embodiment, PSODS is used to vary the position of a poultry house ventilation blocker or door mechanism from a tightly-closed position against the opening, or when required, within a certain range of door mechanism open positions, as dictated by weather conditions or internal air quality. Essentially, the inventive concept featuring PSODS utilizes at least one strap, wherein a first end of each strap is wound about a length of pipe, termed a “pipe drive.” The second end of the strap is attached proximate an upper edge of the door mechanism. As the pipe drive is rotated, the attached strap(s) control movement of the door mechanism toward a closed or open position.