A drawer guide system for a drawer. The drawer guide system includes a drawer guide and a case runner having an outwardly extending flange disposed within an elongate recess of the drawer guide. The drawer guide system further includes a center-mounted bracket to be secured to a rear end of a drawer and a center-mounted release mechanism to be secured to a front end of the drawer that is aligned with the rear end. Upon insertion of the case runner and drawer guide into a recess of the bracket, a tab of the release mechanism engages a window of a side wall of the drawer guide and a locking tang of the drawer guide engages an aperture of the bracket to lock the drawer guide to the drawer.