A route planning system applied in a server or in a mobile client device can plan a travel route according to client device location information. The route planning system includes an obtaining module, a selection module, and a calculation module. The obtaining module obtains the client device location information. The selection module determines a distance or scanning range according to the client device location information, and selects first pictures from the server or the client device of destinations or attractions which are within the scanning range, according to the location information of all the stored pictures. The calculation module calculates at least one route according to the location information of the first pictures. A route planning method is also provided.