Invention Grant
- Patent Title: High sensitivity measurement of parathyroid hormone-related peptide using LC-MS/MS and associated methods
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Application No.: US15150416Application Date: 2016-05-09
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Publication No.: US10241119B2Publication Date: 2019-03-26
- Inventor: Mark M. Kushnir , Alan L. Rockwood , A. Wayne Meikle
- Applicant: University of Utah Research Foundation
- Applicant Address: US UT Salt Lake City
- Assignee: University of Utah Research Foundation
- Current Assignee: University of Utah Research Foundation
- Current Assignee Address: US UT Salt Lake City
- Agency: Thorpe North & Western, LLP
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/78 ; C07K14/635
Abstract:
Methods for measuring and analyzing parathyroid hormone-related peptide (PTHrP) using LC-MS/MS, including applications of the methods thereof, are disclosed and discussed. Such methods can include, along with the use of an isotope-labeled internal standard, purifying PTHrP from a biological sample, proteolytically digesting the PTHrP, and measuring specific digestion products using the using LC-MS/MS.
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