A method of fat suppression during magnetic resonance imaging includes applying a fat suppression module to a region of interest within a subject. The fat suppression module comprises a fat-selective saturation pulse; a first spoiler gradient applied following the fat-selective saturation pulse; a fat-selective inversion pulse applied to the region of interest following a time delay; and a second spoiler gradient applied following the fat-selective inversion pulse. The time delay is selected to allow T1 recovery in the region of interest to a predetermined level of fat magnetization at the end of the time delay. Following application of the fat suppression module, a sequence readout is performed to acquire one or more lines of k-space data covering the region of interest.