Provided are a display substrate, a display panel and a display device, among them, the display substrate includes a base substrate and at least a semiconductor pressure sensor disposed in the display substrate; the semiconductor pressure sensor includes a first connection terminal, a second connection terminal, a third connection terminal and a fourth connection terminal, the first and second connection terminals are used to receive the bias voltage signal, the third and fourth connection terminals are used to output the strain voltage signal; the control electrode arranged at a side of the semiconductor pressure sensor is configured to be insulated with the semiconductor pressure sensor and used to control the semiconductor pressure to be turned on and to be turned off; a control signal line is connected to the control electrode.