Invention Grant
- Patent Title: Flexible tissue matrix and methods for joint repair
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Application No.: US13837849Application Date: 2013-03-15
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Publication No.: US10245306B2Publication Date: 2019-04-02
- Inventor: Mitchell S. Seyedin , Anthony J. Ward , Matthew Matava
- Applicant: ISTO Technologies, Inc.
- Applicant Address: US MO St. Louis
- Assignee: ISTO TECHNOLOGIES II, LLC
- Current Assignee: ISTO TECHNOLOGIES II, LLC
- Current Assignee Address: US MO St. Louis
- Agency: Polsinelli PC
- Main IPC: A61K47/36
- IPC: A61K47/36 ; A61F2/30 ; A61K38/51 ; A61K38/18 ; A61K38/19 ; A61K38/20 ; A61K38/30 ; A61K38/39 ; A61K38/48 ; A61L27/26 ; A61L27/52 ; A61L27/56 ; A61L27/58

Abstract:
A synthetic, flexible tissue matrix and methods for repairing hyaline cartilage defects in a joint using the flexible tissue matrix are described. The flexible tissue matrix includes a high molecular weight polycaprolactone polymer entangled with a polysaccharide such as hyaluronic acid. In the methods, autologous bone mesenchymal stem cells are introduced to a joint by a microfracturing technique, and a membrane made of the flexible matrix is applied to the joint. Cartilage which forms in the joint is hyaline cartilage rather than fibrocartilage.
Public/Granted literature
- US20140142718A1 FLEXIBLE TISSUE MATRIX AND METHODS FOR JOINT REPAIR Public/Granted day:2014-05-22
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