A vacuum bottle sealing apparatus includes a lower unit disposed in an opening of a bottle; an upper unit installed on an upper portion of the lower unit; and a lifting and lowering unit disposed to pass through the lower unit and protrude inwardly of the upper unit from inside of the opening of the bottle. The lifting and lowering unit includes a lifting and lowering bar connected to the upper unit through the lower unit and lifted and lowered by the upper unit; and an elastic sealing ring mounted on an outer circumferential surface of the lifting and lowering bar and sealing am interior of the opening of the bottle as the elastic sealing ring is pressed by the lower unit and then deformed when the lifting and lowering bar is lifted.