Invention Grant
- Patent Title: Preserving genomic connectivity information in fragmented genomic DNA samples
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Application No.: US14572556Application Date: 2014-12-16
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Publication No.: US10246746B2Publication Date: 2019-04-02
- Inventor: Jeffrey S. Fisher , Frank J. Steemers , Sasan Amini , Kevin L. Gunderson
- Applicant: ILLUMINA, INC.
- Applicant Address: US CA San Diego
- Assignee: Illumina, Inc.
- Current Assignee: Illumina, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Fletcher Yoder, P.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6874

Abstract:
A method of sequencing a target nucleic acid polymer by (a) modifying a target nucleic acid polymer to produce a modified nucleic acid polymer; (b) producing fragments of the modified nucleic acid polymer, wherein the fragments are attached to locations on a solid support surface (c) determining nucleotide sequences from the fragments at the locations; and (d) producing a representation of the nucleotide sequence for the target nucleic acid polymer based on the nucleotide sequences from the fragments and the relative distances between the locations on the solid support surface.
Public/Granted literature
- US20150176071A1 PRESERVING GENOMIC CONNECTIVITY INFORMATION IN FRAGMENTED GENOMIC DNA SAMPLES Public/Granted day:2015-06-25
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