Invention Grant
- Patent Title: Method for discrimination of metaplasias from neoplastic or preneoplastic lesions
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Application No.: US15479961Application Date: 2017-04-05
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Publication No.: US10246751B2Publication Date: 2019-04-02
- Inventor: Ruediger Ridder , Magnus Von Knebel Doeberitz , Peter Martin
- Applicant: Ventana Medical Systems, Inc.
- Applicant Address: US AZ Tucson
- Assignee: VENTANA MEDICAL SYSTEMS, INC.
- Current Assignee: VENTANA MEDICAL SYSTEMS, INC.
- Current Assignee Address: US AZ Tucson
- Agency: Ventana Medical Systems, Inc.
- Priority: EP02007954 20020409
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6886 ; G01N33/574 ; C12Q1/70
Abstract:
The present invention relates to a method for discrimination of p16INK4a overexpressing metaplasias from neoplastic or preneoplastic p16INK4a overexpressing lesions by determination of the level of high risk HPV encoded gene-products such as e.g. HPV E2 and/or HPV E7 molecules in biological samples in the course of cytological testing procedures. The method thus enables for reduction of false positive results in the p16INK4a based detection of anogenital lesions in cytological testing procedures.
Public/Granted literature
- US20170268068A1 METHOD FOR DISCRIMINATION OF METAPLASIAS FROM NEOPLASTIC OR PRENEOPLASTIC LESIONS Public/Granted day:2017-09-21
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