Invention Grant
- Patent Title: Materials and methods for diagnosing and predicting the course of prostate cancer
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Application No.: US15271988Application Date: 2016-09-21
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Publication No.: US10247732B2Publication Date: 2019-04-02
- Inventor: Sunil Badve , Harikrishna Nakshatri
- Applicant: Indiana University Research and Technology Corporation
- Applicant Address: US IN Indianapolis
- Assignee: Indiana University Research and Technology Corporation
- Current Assignee: Indiana University Research and Technology Corporation
- Current Assignee Address: US IN Indianapolis
- Agency: Faegre Baker Daniels LLP
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C12Q1/6886 ; G01N33/68
Abstract:
Expression of Forkhead-box protein A1 (FOXA1), a transcription factor important for the normal development of the prostate gland is thought to be controlled by steroid hormones and GATA-3. Expression of FOXA1, GATA-3 and androgen receptor (AR) was retrospectively analyzed by immunohistochemistry (IHC) in a series of 80 primary tumors and 28 metastatic prostate cancers including 15 matched paired samples. High nuclear FOXA1 expression was seen in 19% of primary tumors and 89% of metastatic tumors (p
Public/Granted literature
- US20170030916A1 MATERIALS AND METHODS FOR DIAGNOSING AND PREDICTING THE COURSE OF PROSTATE CANCER Public/Granted day:2017-02-02
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