A glass space partitioning system that is capable of supporting heavy and/or operable glass panels in throughout a range of partially-integrated or fully-integrated configurations, and which integrates an LED-strip light assembly for edge-lighting the glass panels. The system generally includes a framing member comprising a U-shaped horizontal profile with side walls, an intermediate profile attached to the U-shaped profile, a glass pane seated edgewise between a side wall of the U-shaped profile and the intermediate profile, a flexible LED strip cut to length and snap-fit in a vertical orientation against the side wall of the U-shaped profile and adjacent the glass pane for edge lighting, and a cover profile attached to the intermediate profile securing the foregoing.