A power amplification device capable of detaching an element relating to the power amplification of an RF signal from an element relating to the combining of RF signals. The amplifying unit 1 is provided with a plurality of groups of amplifier circuits 2 that amplifies the power of a RF signal and the plurality of groups of amplifier circuits each includes a predetermined number of the amplifier circuits 2. A combining unit 5 includes a first combiner 7 and a second combiner 8. The first combiner 7 is provided in association with the group of the amplifier circuits 2, combines RF signals output from the amplifier circuits 2 belonging to the corresponding group, and outputs the RF signal after combining. The second combiner 8 combines the RF signals output from each first combiner 7 and outputs the RF signal after combining. Each first combiner 7 is a combiner usable for an RF signal in a specific frequency band. The amplifying unit 1 is attachable to and detachable from the combining unit 5.