Disclosed is a method and apparatus for allocating a wireless resource in order to prevent interference in a wireless LAN. A method for allocating a wireless resource in a wireless LAN may comprise the steps of: allocating, by an AP, a plurality of wireless resources for a plurality of STAs included in a BSS, in the entire bandwidth, respectively; and transmitting, by the AP, a PPDU to the plurality of STAs through the plurality of wireless resources, respectively, wherein each of the plurality of wireless resources is a combination of a plurality of wireless units defined in different sizes on a frequency axis, and each of the plurality of wireless resources can be determined in consideration of the size of the bandwidth of at least one STA supporting a bandwidth smaller than the size of the entire bandwidth from among the plurality of STAs.