Invention Grant
- Patent Title: Method for inducing pluripotent stem cells and pluripotent stem cells prepared by said method
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Application No.: US15377464Application Date: 2016-12-13
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Publication No.: US10251824B2Publication Date: 2019-04-09
- Inventor: Ah Reum Kim , Su Na Kim , Won Seok Park , Yoo Wook Kwon , Young Bae Park , Hyo Soo Kim , Jae Seung Paek
- Applicant: AMOREPACIFIC CORPORATION , SNU R&DB FOUNDATION
- Applicant Address: KR Seoul KR Seoul
- Assignee: AMOREPACIFIC CORPORATION,SNU R&DB FOUNDATION
- Current Assignee: AMOREPACIFIC CORPORATION,SNU R&DB FOUNDATION
- Current Assignee Address: KR Seoul KR Seoul
- Agency: Cantor Colburn LLP
- Priority: KR10-2013-0123860 20131017
- Main IPC: A61K8/365
- IPC: A61K8/365 ; A61Q19/00 ; A23L33/105 ; A61K35/28 ; C12N5/074 ; A61K31/191 ; A61K36/14 ; A61Q19/08 ; A61K8/368 ; A61K8/97 ; A23L33/10 ; A23L2/52 ; A61K8/02 ; A61K8/06 ; A61K8/11 ; A61K8/98 ; A61K9/00 ; A61K9/14 ; A61K9/20 ; A61K9/48

Abstract:
The present disclosure relates to a method for inducing pluripotent stem cells by inducing reprogramming and/or dedifferentiation of differentiated adult cells using shikimic acid, a plant extract or plant stem cells containing shikimic acid and an extract of dedifferentiated stem cells (callus), pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells. In accordance with the present disclosure, ethical concerns implicated with the use of eggs to prepare pluripotent stem cells such as embryonic stem cell can be resolved. And, because the plant stem cell extract unharmful to human is used, pluripotent stem cells with proven safety can be prepared and they may be used to develop immunocompatible cell therapy agents suited for individuals. In addition, by pluripotent stem cells from individuals having diseases, the present disclosure will be very useful in studying the cause of diseases and devolving therapeutic strategy.
Public/Granted literature
- US20170128336A1 METHOD FOR INDUCING PLURIPOTENT STEM CELLS AND PLURIPOTENT STEM CELLS PREPARED BY SAID METHOD Public/Granted day:2017-05-11
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