Invention Grant
- Patent Title: Methods of treating fabry patients having renal impairment
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Application No.: US15992336Application Date: 2018-05-30
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Publication No.: US10251873B2Publication Date: 2019-04-09
- Inventor: Jeff Castelli , Elfrida Benjamin
- Applicant: Amicus Therapeutics, Inc.
- Applicant Address: US NJ Cranbury
- Assignee: Amicus Therapeutics, Inc.
- Current Assignee: Amicus Therapeutics, Inc.
- Current Assignee Address: US NJ Cranbury
- Agency: Servilla Whitney LLC
- Main IPC: A61K31/445
- IPC: A61K31/445 ; A61P13/12 ; A61K9/48

Abstract:
Provided are methods for treatment of Fabry disease in a patient having renal impairment and/or elevated proteinuria. Certain methods comprise administering to the patient about 100 to about 150 mg free base equivalent of migalastat or salt thereof at a frequency of once every other day. Certain methods also provide for the stabilization of renal function, reducing left ventricular mass index, reducing plasma globotriaosylsphingosine and/or increasing α-galactosidase A activity in the patient.
Public/Granted literature
- US20180344712A1 Methods Of Treating Fabry Patients Having Renal Impairment Public/Granted day:2018-12-06
Information query
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