Invention Grant
- Patent Title: Retro-inverso analogs of spadin display increased antidepressant effects
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Application No.: US15114241Application Date: 2015-01-27
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Publication No.: US10251937B2Publication Date: 2019-04-09
- Inventor: Georges Gaudriault , Catherine Heurteaux , Jean Mazella , Marc Borsotto , Hamid Moha Ou Maati , Julie Veyssiere
- Applicant: MEDINCELL , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Applicant Address: FR Jacou FR Paris
- Assignee: MEDINCELL,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: MEDINCELL,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Jacou FR Paris
- Agency: Kusner & Jaffe
- International Application: PCT/IB2015/000338 WO 20150127
- International Announcement: WO2015/110915 WO 20150730
- Main IPC: A61K38/08
- IPC: A61K38/08 ; A61K38/10 ; A61K38/17 ; A61K47/60
Abstract:
Compositions, pharmaceutical compositions and biodegradable pharmaceutical compositions containing at least one analog of spadin or at least one analog of a propeptides of spadin or mixtures thereof are described. Methods for treating depression using the analogs of spadin or analogs of propeptides of spadin or mixtures thereof, as well as methods for blocking TREK-1 channel activity are also disclosed.
Public/Granted literature
- US20170072013A1 RETRO-INVERSO ANALOGS OF SPADIN DISPLAY INCREASED ANTIDEPRESSANT EFFECTS Public/Granted day:2017-03-16
Information query
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