Invention Grant
- Patent Title: Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine
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Application No.: US14602065Application Date: 2015-01-21
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Publication No.: US10251948B2Publication Date: 2019-04-09
- Inventor: Yiming Shao , Lianxing Liu , Rongxian Shen
- Applicant: NATIONAL CENTER FOR AIDS/STD CONTROL AND PREVENTION, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION
- Applicant Address: CN Beijing
- Assignee: National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention
- Current Assignee: National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention
- Current Assignee Address: CN Beijing
- Agency: Alston & Bird LLP
- Priority: CN200810097471 20080527
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C07K14/005 ; C07K16/10 ; C12N7/00 ; A61K39/12 ; A61K39/00
Abstract:
Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
Public/Granted literature
- US20150132332A1 Anti-HIV Vaccine Constructed Based on Amino Acid Mutations in Attenuated Live EIAV Vaccine Public/Granted day:2015-05-14
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