Invention Grant
- Patent Title: Stabilized HIV-1 peptide constructs comprising the gp120 C5 domain and gp41 hydrophilic domain
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Application No.: US14952292Application Date: 2015-11-25
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Publication No.: US10251949B2Publication Date: 2019-04-09
- Inventor: Maja Sommerfelt Grønvold , Angus Dalgleish , Einar Tønnes Lange , Jens Olof Holmberg , Per Bengtsson , Birger Sørensen
- Applicant: Bionor Immuno AS
- Applicant Address: NO Skien
- Assignee: BIONOR IMMUNO AS
- Current Assignee: BIONOR IMMUNO AS
- Current Assignee Address: NO Skien
- Agency: Womble Bond Dickinson (US) LLP
- Priority: EP09164565 20090703
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C07K14/005 ; C07K16/10 ; A61K39/12 ; C12N7/00 ; A61K39/00
Abstract:
Disclosed is a method for treatment of HIV related diseases comprising targeting complexes between on the one hand the C5 domain of gp120 and on the other hand gp41 or the C2 domain of gp120. The complexes may be stabilised by administering compounds, such as antibodies, capable of directly interacting with and stabilising the complex, or by immunizing with C5 and gp41/C2 derived material so as to induce antibodies that bind to and stabilise the complex.
Public/Granted literature
- US20160144019A1 Novel Therapeutic and Diagnostic Means Public/Granted day:2016-05-26
Information query
