Invention Grant
- Patent Title: Methods of making pharmaceutical compositions with enhanced stability
-
Application No.: US15661066Application Date: 2017-07-27
-
Publication No.: US10251956B2Publication Date: 2019-04-09
- Inventor: Yuhua Li , Benjamin Chien
- Applicant: Foresee Pharmaceuticals Co., Ltd.
- Applicant Address: TW Taipei
- Assignee: Foresee Pharmaceuticals Co., Ltd.
- Current Assignee: Foresee Pharmaceuticals Co., Ltd.
- Current Assignee Address: TW Taipei
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A61K47/34
- IPC: A61K47/34 ; A61K38/09 ; A61K9/00 ; A61K38/22 ; A61K47/22

Abstract:
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analog formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.
Public/Granted literature
- US20180050108A1 Methods of Making Pharmaceutical Compositions with Enhanced Stability Public/Granted day:2018-02-22
Information query
IPC分类: