A tamper-evident closure for a container. The closure comprises a first portion including inner and outer parts, and a second portion. The outer part is rotatable relative to the inner part from a first position in which at least part of the first and second portions are adjacent each other to a second position in which there is a gap therebetween. The first portion comprises a locking mechanism for irreversibly locking the closure in the second position upon first opening so that the gap cannot be closed, in which the first portion comprises a compressible stopper for sealing the second portion and/or the container. A tamper-evident closure in combination with a container.