A self-homing hoist includes a controller configured to initiate a self-homing process to return the hook assembly to a homed position in response to each of at least one homing factor being true. Each homing factor is true or false based on a comparison of the current condition of the homing factor with a threshold requirement. If the current condition satisfies the threshold requirement, then the homing factor is true. If the current condition does not satisfy the threshold requirement, then the homing factor is false. Where all homing factors are true, the controller can initiate the self-homing process by activating a hoist motor to drive the cable drum and reel the hook assembly into the homed position.