Invention Grant
- Patent Title: Crystalline form of atorvastatin hemi-calcium salt, hydrate thereof, and method of producing the same
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Application No.: US15441430Application Date: 2017-02-24
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Publication No.: US10252993B2Publication Date: 2019-04-09
- Inventor: Kyung Ju Lee , Hoe Joo Son , Doo Seong Choi , Sun Ho Chang , Do Yeon Oh
- Applicant: KYONGBO PHARM
- Applicant Address: KR Asan-si
- Assignee: KYONGBO PHARM
- Current Assignee: KYONGBO PHARM
- Current Assignee Address: KR Asan-si
- Agency: Heslin Rothenberg Farley & Mesiti, P.C.
- Agent Philip Hansen
- Priority: KR10-2010-0072991 20100728
- Main IPC: C07D207/34
- IPC: C07D207/34
Abstract:
The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
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