Invention Grant
- Patent Title: Spiro-lactam NMDA receptor modulators and uses thereof
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Application No.: US15653738Application Date: 2017-07-19
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Publication No.: US10253032B2Publication Date: 2019-04-09
- Inventor: John A. Lowe, III , M. Amin Khan
- Applicant: Aptinyx Inc.
- Applicant Address: US IL Evanston
- Assignee: Aptinyx Inc.
- Current Assignee: Aptinyx Inc.
- Current Assignee Address: US IL Evanston
- Agency: Goodwin Procter LLP
- Main IPC: C07D487/10
- IPC: C07D487/10

Abstract:
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
Public/Granted literature
- US20180155354A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF Public/Granted day:2018-06-07
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