Invention Grant
![7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds and their use as mutant IDH1 inhibitors](/docs/US/2019-04-09/US10253041B2/abs.jpg.600x600.jpg)
- Patent Title: 7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds and their use as mutant IDH1 inhibitors
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Application No.: US15570759Application Date: 2016-07-21
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Publication No.: US10253041B2Publication Date: 2019-04-09
- Inventor: Renato A. Bauer , Serge Louis Boulet , Timothy Paul Burkholder , Santiago Carballares Martin , James Ronald Gillig , Raymond Gilmour , Wenceslao Lumeras , Zhipei Wu
- Applicant: Eli Lilly and Company
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Grant E Reed
- Priority: EP15382386 20150727; EP15382606 20151204
- International Application: PCT/US2016/043264 WO 20160721
- International Announcement: WO2017/019429 WO 20170202
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/5365 ; C07D498/04 ; C07D519/00 ; A61P35/02 ; A61P35/00
![7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds and their use as mutant IDH1 inhibitors](/abs-image/US/2019/04/09/US10253041B2/abs.jpg.150x150.jpg)
Abstract:
Phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds of Formula I, formulations containing those compounds, and their use as mutant isocitrate dehydrogenase 1 enzyme inhibitors.
Public/Granted literature
- US20180118759A1 7-PHENYLETHYLAMINO-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE COMPOUNDS AND THEIR USE AS MUTANT IDH1 INHIBITORS Public/Granted day:2018-05-03
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