Invention Grant
- Patent Title: HBED-bisphosphonates, radiometal conjugates and their use as theranostic agents
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Application No.: US15203602Application Date: 2016-07-06
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Publication No.: US10253052B2Publication Date: 2019-04-09
- Inventor: Hank F. Kung , Zehui Wu , Seok Rye Choi , Karl Plössl , Zhihao Zha
- Applicant: Five Eleven Pharma Inc.
- Applicant Address: US PA Philadelphia
- Assignee: Five Eleven Pharma Inc.
- Current Assignee: Five Eleven Pharma Inc.
- Current Assignee Address: US PA Philadelphia
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K51/04
- IPC: A61K51/04 ; A61K49/10 ; C07F9/38 ; C07F9/6515 ; C07F9/6524
Abstract:
The present invention relates to compounds according to Formula I or Formula II, which are potential bone imaging agents. Certain compounds labeled with 68Ga displayed excellent bone uptake and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula I or Formula II or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20170022224A1 HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents Public/Granted day:2017-01-26
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