Invention Grant
- Patent Title: WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide
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Application No.: US15121525Application Date: 2015-02-26
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Publication No.: US10253075B2Publication Date: 2019-04-09
- Inventor: Takashi Nishimura , Yuji Heike , Yuji Togashi
- Applicant: Tella, Inc.
- Applicant Address: JP Tokyo
- Assignee: TELLA, INC.
- Current Assignee: TELLA, INC.
- Current Assignee Address: JP Tokyo
- Agency: RatnerPrestia
- Priority: JP2014-035893 20140226
- International Application: PCT/JP2015/055546 WO 20150226
- International Announcement: WO2015/129790 WO 20150903
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07K14/47 ; A61K39/00 ; C07K7/06 ; C07K7/08 ; C07K14/00 ; C12N5/0783 ; A61K38/00

Abstract:
[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against numerous types of cancers.[Solution] Provided is a fused polypeptide that includes a helper epitope derived from the WT1 protein, and a killer epitope derived from the WT1 protein, wherein the polypeptide includes a total of 3 to 6 of the helper epitopes and the killer epitopes per molecule of the fused polypeptide.
Public/Granted literature
- US20160362465A1 WT1 ANTIGENIC POLYPEPTIDE, AND ANTI-TUMOR AGENT CONTAINING SAID POLYPEPTIDE Public/Granted day:2016-12-15
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