Invention Grant
- Patent Title: CD31 peptides for the treatment of thrombotic or autoimmune disorders
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Application No.: US14809603Application Date: 2015-07-27
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Publication No.: US10253085B2Publication Date: 2019-04-09
- Inventor: Giuseppina Caligiuri , Antonino Nicoletti
- Applicant: Giuseppina Caligiuri , Antonino Nicoletti
- Applicant Address: FR Paris
- Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- Current Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
- Current Assignee Address: FR Paris
- Agency: W&C IP
- Priority: EP08305360 20080630
- Main IPC: A61K38/03
- IPC: A61K38/03 ; C07K4/00 ; C07K7/00 ; C07K14/705 ; G01N33/50 ; A61K38/00
Abstract:
The present invention stems from the finding that the extracellular domain of CD31 proteins present on blood leukocytes is shed and released in the circulation as a soluble form of CD31. The invention relates to peptides corresponding to fragments of CD31 that inhibit T-cell response, and to their use in the treatment of thrombotic disorders such as atherothrombosis and autoimmune disorders.
Public/Granted literature
- US20150376258A1 USE OF CD31 PEPTIDES IN THE TREATMENT OF THROMBOTIC AND AUTOIMMUNE DISORDERS Public/Granted day:2015-12-31
Information query
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