Invention Grant
- Patent Title: Modified beta-lactamases and methods and uses related thereto
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Application No.: US15661416Application Date: 2017-07-27
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Publication No.: US10253306B2Publication Date: 2019-04-09
- Inventor: Pertti Koski , Ulla Airaksinen , Katja Valimaki
- Applicant: Synthetic Biologics, Inc.
- Applicant Address: US MD Rockville
- Assignee: SYNTHETIC BIOLOGICS, INC.
- Current Assignee: SYNTHETIC BIOLOGICS, INC.
- Current Assignee Address: US MD Rockville
- Agency: Morgan, Lewis & Bockius LLP
- Priority: FI20105572 20100524
- Main IPC: C12N9/86
- IPC: C12N9/86 ; A61K38/50 ; A61K31/43 ; A61K31/545 ; A61K45/06 ; A61K9/00 ; A61K9/48 ; A61K38/00
Abstract:
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects.Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide.
Public/Granted literature
- US20170327812A1 MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO Public/Granted day:2017-11-16
Information query
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