Invention Grant
- Patent Title: DNA-binding proteins and uses thereof
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Application No.: US15709969Application Date: 2017-09-20
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Publication No.: US10253333B2Publication Date: 2019-04-09
- Inventor: Philip D. Gregory , Jeffrey C. Miller , David Paschon , Edward J. Rebar , Siyuan Tan , Fyodor Urnov , Lei Zhang
- Applicant: Sangamo Therapeutics, Inc.
- Applicant Address: US CA Richmond
- Assignee: Sangamo Therapeutics, Inc.
- Current Assignee: Sangamo Therapeutics, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law
- Agent Susan Abrahamson
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N15/52 ; C12N15/90 ; C12N15/62 ; C12N15/85 ; C07K14/195 ; C12N15/82 ; A61K38/00
Abstract:
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
Public/Granted literature
- US20180010152A1 NOVEL DNA-BINDING PROTEINS AND USES THEREOF Public/Granted day:2018-01-11
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