Invention Grant
- Patent Title: Multiplex PCR to detect gene fusions
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Application No.: US15130486Application Date: 2016-04-15
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Publication No.: US10253349B2Publication Date: 2019-04-09
- Inventor: Ann Begovich , Rajiv Dua , Dwight Kuo , Xiaoju Max Ma , Ellen Ordinario
- Applicant: Roche Molecular Systems, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Molecular Systems, Inc.
- Current Assignee: Roche Molecular Systems, Inc.
- Current Assignee Address: US CA Pleasanton
- Agent Carol Johns
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6806 ; C12Q1/6809 ; C12Q1/6858 ; C12Q1/686
Abstract:
Provided herein are methods and compositions for detecting gene fusions, e.g., relevant to cancer. The present methods and compositions can be used to detect gene fusions with very high sensitivity and specificity. The present methods and compositions can detect gene fusions, e.g., in free circulating tumor RNA from a plasma sample.
Public/Granted literature
- US20160304937A1 MULTIPLEX PCR TO DETECT GENE FUSIONS Public/Granted day:2016-10-20
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