Invention Grant
- Patent Title: BNA clamp method
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Application No.: US14431380Application Date: 2013-09-27
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Publication No.: US10253360B2Publication Date: 2019-04-09
- Inventor: Takeshi Imanishi , Ayako Orita , Ikuya Ban
- Applicant: BNA INC.
- Applicant Address: JP Ibaraki
- Assignee: BNA INC.
- Current Assignee: BNA INC.
- Current Assignee Address: JP Ibaraki
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2012-217657 20120928
- International Application: PCT/JP2013/076329 WO 20130927
- International Announcement: WO2014/051076 WO 20140403
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6858 ; C07H19/06 ; C07H19/16 ; C07H21/02 ; C07H21/04

Abstract:
The invention provides a method of selectively amplifying a detection target nucleic acid by inhibiting amplification of a detection non-target nucleic acid (e.g., wild-type gene) in a test sample by using, in a nucleic acid amplification reaction, an oligonucleotide analog containing one or more kinds of one or more unit structures of various nucleoside analogs represented by the following formula (I): wherein the symbols are as defined in the DESCRIPTION, and the like, or a salt thereof, as a clamp nucleic acid, and detecting the amplified nucleic acid.
Public/Granted literature
- US20150240299A1 BNA CLAMP METHOD Public/Granted day:2015-08-27
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