A method of analyzing a skin-print provided on a first surface of an optically transparent substrate. The method comprises the steps of exposing the skin-print on the first surface of the optically transparent substrate to one or more reagents selected to bind with one or more metabolites present in the skin-print; transmitting electromagnetic radiation onto the skin-print through the optically transparent substrate using a radiation source to thereby produce an optical signal of said one or more reagents and/or said one or more metabolites; and detecting an optical image of the optical signal through the optically transparent substrate using a sensor. Also a skin-print analysis apparatus and a reagent cartridge for use in carrying out the method.