The present disclosure relates to a field of display device and provides a flexible display panel, a method of preparing the same and a flexible display device. The flexible display panel includes: at least two sub-flexible display panels, each two adjacent sub-flexible display panels being connected together through a folding mechanism therebetween, the flexible display panel further including a flexible light guide structure that at least covers the folding mechanism, the flexible light guide structure being configured to emit a portion of light emitted from each sub-flexible display panel out of a portion of the flexible light guide structure that corresponds to the folding mechanism.