A method for generating unique identifiers for programmable mobile machines may include (1) receiving data for generating a unique signature and (2) generating the unique signature based on the data. The unique signature may identify a programmable mobile machine from among a group of programmable mobile machines within a machine environment. A corresponding method for tracking unique identifiers for programmable mobile machines may include (1) receiving a unique signature generated by a programmable mobile machine, (2) associating the unique signature with metrics, in a database, that correspond to identification data for each of a group of programmable mobile machines, and (3) determining an identity of the programmable mobile machine based on the unique signature matching at least one of the metrics in the database. Various other methods and systems are also disclosed.