An information processing system includes: an information acquisition unit that acquires traveling area information of the vehicle; an entry determination unit that determines whether the vehicle has entered a specific range; an area information storage unit that stores the traveling area information when the vehicle has entered the specific range; a reception unit that receives a stop signal including information on a stop position of a different vehicle different from the vehicle when the different vehicle stops traveling or is in a state difficult to continue normally traveling; a relation determination unit that determines a positional relationship between the different vehicle and the vehicle, based on the information on the stop position and the traveling area information; and a processing execution unit that executes a predetermined process in accordance with a determination result.