Invention Grant
- Patent Title: Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy
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Application No.: US15308652Application Date: 2015-05-06
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Publication No.: US10258639B2Publication Date: 2019-04-16
- Inventor: Marc Montminy , Sam Van De Velde , Emilie Blanchet
- Applicant: Research Development Foundation
- Applicant Address: US NV Carson City
- Assignee: Research Development Foundation
- Current Assignee: Research Development Foundation
- Current Assignee Address: US NV Carson City
- Agency: Parker Highlander PLLC
- International Application: PCT/US2015/029411 WO 20150506
- International Announcement: WO2015/171723 WO 20151112
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/713 ; A61K38/26 ; A61K31/436 ; A61K31/565 ; C12N5/00
Abstract:
Methods for treatment of insulin resistance and type II diabetes by administration of inhibitors of the PKI pathway are provided. In some aspects, inhibitors of the PKI pathway, such as inhibitors of PIKB, HIF1 and/or mTOR, can be used to treat subject having insulin resistance who are refractory to GLP1 agonist therapy.
Public/Granted literature
- US20170189440A1 METHODS FOR TREATING INSULIN RESISTANCE AND FOR SENSITIZING PATIENTS TO GLP1 AGONIST THERAPY Public/Granted day:2017-07-06
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