Invention Grant
- Patent Title: Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists
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Application No.: US15784560Application Date: 2017-10-16
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Publication No.: US10259787B2Publication Date: 2019-04-16
- Inventor: Giles Albert Brown , Miles Stuart Congreve , Mark Pickworth , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Welwyn Garden
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Welwyn Garden
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Main IPC: A61K31/015
- IPC: A61K31/015 ; C07C211/35 ; C07D207/14 ; C07D401/08 ; C07D403/04 ; C07D471/10 ; C07D243/08 ; C07D409/08 ; C07D413/14 ; C07D471/04 ; C07D487/04 ; C07D413/12 ; C07D271/06 ; C07D413/04 ; C07D487/10 ; C07D209/96 ; C07D295/205 ; C07D213/57
Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor or M1 and M4 receptors and which are useful in the treatment of muscarinic M1 or M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula wherein Q4, Q5, R5, p, V, Q1, Q2, X1, X2 and W are defined herein.
Public/Granted literature
- US20180105491A1 PHARMACEUTICAL COMPOUNDS Public/Granted day:2018-04-19
Information query
