Invention Grant
- Patent Title: Methods of producing and characterizing virus vaccine and virus vaccine composition
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Application No.: US16125492Application Date: 2018-09-07
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Publication No.: US10260050B2Publication Date: 2019-04-16
- Inventor: Dianlian Liu , Wen Ai , Mingfeng Shen
- Applicant: Guangzhou Realbenefitspot Pharmaceutical Co., Ltd.
- Applicant Address: CN Guangzhou
- Assignee: Guangzhou Realbenefitspot Pharmaceutical Co., Ltd.
- Current Assignee: Guangzhou Realbenefitspot Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Guangzhou
- Agency: Morrison & Foerster LLP
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K39/12 ; C07K1/18 ; C07K1/20 ; C07K1/22 ; C07K1/36 ; C07K14/005 ; C12N7/02 ; B01D15/36 ; B01J20/04 ; G01N30/02

Abstract:
This application pertains to methods of isolating virus particles and producing virus vaccine composition comprising subject a biological sample to an anion exchange chromatography and a hydroxyapatite chromatography. The application also pertains to rabies virus vaccine compositions and methods of assessing suitability of a virus vaccine composition or releasing a commercial batch of virus vaccine composition for clinical use.
Public/Granted literature
- US20190002839A1 METHODS OF PRODUCING AND CHARACTERIZING VIRUS VACCINE AND VIRUS VACCINE COMPOSITION Public/Granted day:2019-01-03
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