Invention Grant
- Patent Title: DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
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Application No.: US14820254Application Date: 2015-08-06
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Publication No.: US10260094B2Publication Date: 2019-04-16
- Inventor: Jingyue Ju , Dae Hyun Kim , Jia Guo , Qinglin Meng , Zengmin Li , Huanyan Cao
- Applicant: Jingyue Ju , Dae Hyun Kim , Jia Guo , Qinglin Meng , Zengmin Li , Huanyan Cao
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White; Gary J. Gershik
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6874 ; C07H19/04 ; C12Q1/6869 ; C12Q1/6876 ; A61K31/70
Abstract:
This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogs or 3′ modified deoxyinosine triphosphate analogs, and 3′ modified dideoxynucleotide analogs having a detectable marker attached to a base thereof.
Public/Granted literature
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